IVF: same chances of pregnancy with fresh or frozen embryos

According to 2 studies published in the New England Journal of Medicine, the success rate for women using in vitro fertilization (IVF) is the same whether the embryos are fresh or frozen.

Women using in vitro fertilization can be transferred fresh embryos ", that is to say obtained during the current stimulation and performed in vitro, or frozen, that is to say embryos obtained during previous ovarian stimulation, or, for example, ovarian toxicity chemotherapy.
An international team of researchers compared the success rate for these two types of embryos. And the results of the study are published by the New England Journal of Medicine.

Differences according to the ovulation of the woman

The success rate is similar but only if women have normal ovulation. Because sterility can be caused by a multitude of problems, including weight problems, stress or poor lifestyle.
2157 women with normal ovulation participated in the study. They were drawn to receive their fresh or frozen embryos. There is no difference in the birth rate: 48.8% for frozen embryos. 50.2% for fresh embryos (the figures are not statistically different).

Adapt the type of IVF to each patient

In contrast, in women with polycystic ovary syndrome, the use of frozen embryos increases the chances of pregnancy and birth.
"This is an important and distinct conclusion from our previous study on IVF. She suggests that one type of IVF is not suitable for all women, so it should be based on the specific characteristics of the patient, "says Richard S. Legro, professor of obstetrics and gynecology at Penn State College of Medicine. .

Fewer complications with frozen embryos

From the point of view of preventing the complications of ovarian stimulation and IVF, however, researchers favor frozen embryos.
With these, there is less risk of developing ovarian hyperstimulation syndrome (OHSS), a fairly common complication that can lead to weight gain, large fluid effusions or kidney failure. In the most serious cases, there is even a risk of serious illness or death.

Video: Embryo Transfer, Cryopreservation & IVF Results - Zain Al-Safi, MD. UCLA Health Fertility Clinic (April 2020).