Dementia: a healthy lifestyle would reduce the risks in predisposed people

Having a healthy lifestyle could allow people who are genetically predisposed to reduce the risk of dementia by 32%.

At present, 50 million people are living with dementia worldwide. According to the Medical Research Foundation (FRM), the number of cases is expected to nearly double every 20 years, particularly because of the aging of the population. Among these patients, 60 to 70% suffer from Alzheimer's disease (900,000 patients are affected in France), which is most often manifested by memory problems. The accomplishment of daily tasks then becomes more difficult and adapt to new situations almost impossible, the relationship to time and places being more and more confused.

However, according to a study published in the journal JAMA Network and presented at the International Association of Alzheimer's Conference in Los Angeles, USA, adopting a healthy lifestyle could reduce the risk of dementia by 32% in people at risk.

Researchers from the University of Exter, Oxford (United Kingdom), Michigan (United States) and South Australia (Australia) analyzed data from 196,383 adults of European ancestry aged 60 years and older. They identified 1,769 cases of dementia over an eight-year follow-up period. In the course of their study, they divided the participants into three groups: the first presented strong genetic risks of dementia, the second the intermediate risks and the third the low risks.

A study that goes against "the fatalistic image of dementia"

To examine the lifestyle of the people followed, the researchers also grouped them into the "favorable", "intermediate" and "unfavorable" categories according to their diet, their physical activity and their consumption of cigarettes and cigarettes. alcohol. Race Result: Healthy living was associated with a lower risk of dementia in all genetically-at-risk groups. In detail, participants with a high genetic risk and a poor lifestyle were almost three times more likely to develop dementia than those with low genetic risk and leading a healthy lifestyle.

"This is the first study that shows how much you can reduce your genetic risk of dementia by living a healthy lifestyle, and our discoveries are exciting because they show that we can take action to reduce our genetic risk of dementia." a healthy lifestyle was associated with a reduced risk of dementia regardless of the genetic risk, "says Dr. Elbieta Kuma of the University of Exter School of Medicine who conducted the study.

"This research delivers an important message that goes against the fatalistic image of dementia.Many people believe that they will inevitably fall into dementia because of their genes.However, it is proven that you can substantially reduce your risk of dementia by having a healthy lifestyle ", adds his colleague Dr. David Llewellyn.

Sport to slow brain decline

However, other studies have already shown that it is possible to reduce the risk of dementia by taking care of his lifestyle. Several studies have shown the impact of sport on cognitive impairment. Indeed, irisine, a hormone and protein released by physical exercise, would help strengthen his memory in the short term, preventing brain decline.

In April, researchers also discovered that even diet can change the progression of the disease. According to work published in the Journal of The Alzheimer's Diseasea ketogenic diet, low in carbohydrates and high in fat, could indeed boost the cognitive reflexes of people showing early signs of dementia.

Video: alzheimers and dementia. 10 Things to Do to Prevent Alzheimers Disease - alzheimers disease (February 2020).